Supporting information for: Electrostatic Binding and Hydrophobic Collapse of Peptide-Nucleic Acid Aggregates Quantified Using Force Spectroscopy
نویسندگان
چکیده
Small Biosystems Lab, Departament de Física Fonamental, Universitat de Barcelona, Avda. Diagonal 647, 08028 Barcelona, Spain, CIBER de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Madrid, Spain, Centro Nacional de Biotecnología, CSIC, 28049 Cantoblanco, Madrid, Spain, Institut de Química Avançada de Catalunya, Consejo Superior de Investigaciones Científicas (IQAC-CSIC), 08034 Barcelona, Spain, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Science Park, Baldiri Reixac 10-12, 08028 Barcelona, Spain, Department of Organic Chemistry, University of Barcelona, 08028. Barcelona, Spain, and School of Chemsitry and Physics, University of KwaZulu-Natal, 4001-Durban, South Africa
منابع مشابه
Electrostatic binding and hydrophobic collapse of peptide-nucleic acid aggregates quantified using force spectroscopy.
Knowledge of the mechanisms of interaction between self-aggregating peptides and nucleic acids or other polyanions is key to the understanding of many aggregation processes underlying several human diseases (e.g., Alzheimer's and Parkinson's diseases). Determining the affinity and kinetic steps of such interactions is challenging due to the competition between hydrophobic self-aggregating force...
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